Organonitrogen Compounds
Aobchem 4-(Methoxymethyl)- -methylbenzenemethanol | ≥95% | CAS 66190-31-6 | C10H14O2 | 250mg
4-(Methoxymethyl)- -methylbenzenemethanol | ≥95% | CAS 66190-31-6 | C10H14O2 | 250mg
Aobchem 3-Bromo-N-methoxy-N-methylbenzamide | ≥97% | CAS 207681-67-2 | C9H10BrNO2 | 1g
3-Bromo-N-methoxy-N-methylbenzamide | ≥97% | CAS 207681-67-2 | C9H10BrNO2 | 1g
Aobchem 5-(Hydroxymethyl)-2-methylbenzonitrile | ≥97% | CAS 315188-34-2 | C9H9NO | 1g
5-(Hydroxymethyl)-2-methylbenzonitrile | ≥97% | CAS 315188-34-2 | C9H9NO | 1g
Aobchem 5-Bromo-2-hydroxy-4-methylbenzaldehyde | ≥97% | CAS 311318-63-5 | C8H7BrO2 | 500mg
5-Bromo-2-hydroxy-4-methylbenzaldehyde | ≥97% | CAS 311318-63-5 | C8H7BrO2 | 500mg
Aobchem 5-Chloro-2-ethoxy-3-methylbenzaldehyde | 95% | CAS 708984-80-9 | C10H11ClO2 | 1g
5-Chloro-2-ethoxy-3-methylbenzaldehyde | 95% | CAS 708984-80-9 | C10H11ClO2 | 1g
Aobchem 2-Chloro-3-fluoro-4-methylbenzaldehyde | ≥97% | CAS 1785126-63-7 | C8H6ClFO | 1g
2-Chloro-3-fluoro-4-methylbenzaldehyde | ≥97% | CAS 1785126-63-7 | C8H6ClFO | 1g
eMolecules 1195-45-5 | 4-Fluorophenyl isocyanate | Chem-Impex | MFCD00002023 | 137.113 | C7H4FNO | 98.000 | Fc1ccc(cc1)N=C=O | 5g | 650585524
4-Fluorophenyl isocyanate | Chem-Impex | 1195-45-5 | MFCD00002023 | 137.113 | C7H4FNO | 98.000 | Fc1ccc(cc1)N=C=O | 5g | 650585524
Aobchem 2-Chloro-4-fluoro-3-methylbenzoic acid | ≥97% | CAS 173315-54-3 | C8H6ClFO2 | 250mg
2-Chloro-4-fluoro-3-methylbenzoic acid | ≥97% | CAS 173315-54-3 | C8H6ClFO2 | 250mg
Medchemexpress LLC XL-3158 | 3117797-77-7 | 99.55% | 690.61 | 50 MG
XL-3158 is a selective, cross-species Cyclic GMP-AMP synthase (cGAS) inhibitor. It has an IC50 of 11.1 μM for human cGAS and 2.19 μM for mouse cGAS. This compound simultaneously occupies allosteric and orthosteric sites, stabilizing the activation loop in a closed, inactive conformation, which attenuates cGAS-DNA interactions. XL-3158 inhibits cGAS by targeting phase separation, efficiently penetrating cells by inhibiting aggregate formation and reducing the local concentration of cGAS within cells. It is suitable for studying cGAS-dependent inflammatory diseases.
- Selective and cross-species cGAS inhibitor.
- Inhibits cGAS by targeting phase separation.
- Efficiently penetrates cells by inhibiting aggregate formation.
- Reduces local concentration of cGAS within cells.
- Can be used for the study of cGAS-dependent inflammatory diseases.
Cambridge Isotope Laboratories Isophorone (3-methyl-D3 2 4 4 6 6-D5 97%) 0 1 g
Isophorone (3-methyl-D3 2 4 4 6 6-D5 97%) 0 1 g
Medchemexpress LLC XL-3158 | 99.6% | 690.61 g/mol | C30H17F7N6O2S2 | 10 MG
XL-3158 is a selective, cross-species inhibitor of cyclic GMP-AMP synthase (cGAS) for research applications. It binds both allosteric and orthosteric sites to stabilize the activation loop in an inactive conformation, reducing cGAS-DNA interactions and phase separation. The compound shows cellular activity with limited cytotoxicity at effective concentrations and is suitable for studies of cGAS-dependent inflammatory pathways.
- Selective cross-species inhibition of cGAS
- Dual-site binding stabilizes inactive activation loop
- Reduces cGAS-DNA interactions and phase separation
- Demonstrated cellular activity with low cytotoxicity
- High purity suitable for cell-based assays
Cayman Chemical 11 12EpETE Fatty Acids and Der
An epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo; its effects of remain to be determined
Aobchem 1 1-Dimethylethyl 2-methylbenzoate | ≥95% | CAS 16537-18-1 | C12H16O2 | 250mg
1 1-Dimethylethyl 2-methylbenzoate | ≥95% | CAS 16537-18-1 | C12H16O2 | 250mg
Aobchem 2-Bromo-5-methoxy-N-methylbenzamide | ≥95% | CAS 171425-69-7 | C9H10BrNO2 | 5g
2-Bromo-5-methoxy-N-methylbenzamide | ≥95% | CAS 171425-69-7 | C9H10BrNO2 | 5g
Aobchem 4-Bromo-2-hydroxy-6-methylbenzoic acid | ≥95% | CAS 2091785-59-8 | C8H7BrO3 | 500mg
4-Bromo-2-hydroxy-6-methylbenzoic acid | ≥95% | CAS 2091785-59-8 | C8H7BrO3 | 500mg